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PURE - anti mouse KLRG1 - Clone 2F1

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PURE - anti mouse KLRG1 - Clone 2F1

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PURE - anti Mouse KLRG1 - 2F1

Reference	Size	Price	Quantity	Add to cart
MOKLRPU(V100)	100 μg	120,00 € tax excl.	The minimum purchase order quantity for the product is 1
MOKLRPU(V500)	500 μg	400,00 € tax excl.	The minimum purchase order quantity for the product is 1

Reference

Size

Price

Quantity

Add to cart

MOKLRPU(V100)

100 μg

120,00 € tax excl.

MOKLRPU(V500)

500 μg

400,00 € tax excl.

Product Description

Clone: 2F1
Isotype: Mouse IgG2a
Tested Applications: Flow Cytometry
Conjugated: PURE
Concentration: 0.5 mg/ml
Immunogen: A-LAK from C57BL/6 mice
Species Reactivity: Mouse
Storage Buffer: The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium azide (NaN3)
Regulatory Status: RUO
Presentation: Liquid
Storage Instruction: Store in the dark at 2-8 °C

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Large description: Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag). KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3. It is composed of a homodimer of glycosylated 30-38 kD subunits. Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymph okine-activated killer (LAK) cells but not mast cells. KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells. KLRG1 may be involved in regulating NK cell homeostasis. KLRG1 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

Other names: MAFA, 2F1-Ag
GeneID:
Molecular weight: 30-38 kD