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品牌：List Labs 

貨號(hào)：106

品名：List Labs Cholera Toxin B Subunit (CTB) from Vibrio cholerae FITC, Conjugate

中文名：

規(guī)格：0.2 mg

形式：lyophilized powder

儲(chǔ)存溫度：4°C

描述：

Cholera toxin is an oligomeric protein of MW 84,000 daltons which consists of a single A subunit surrounded by five B subunits.  It is a potent activator of adenylate cyclase and is the pathogenic agent responsible for the symptoms of cholera.  The B subunit (a.k.a. choleragenoid) is responsible for the binding of the holotoxin to GM1 ganglioside receptors on mammalian cell surfaces  and facilitates entry of the A subunit into the cell. The A subunit bears the ADP-ribosyl-transferase activity, which deregulates the Gs protein causing activation of adenylate cyclase.  Due to the ubiquitous occurrence of the GM1 ganglioside receptor on eukaryotic cell membranes, cholera toxin activates adenylate cyclase in a wide variety of model systems。

注：產(chǎn)品僅用于研究目的，不得用于人體或作為診斷劑。