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A potent inhibitor of IgE-mediated mast cell responses to allergens in vitro and in vivo. Also inhibits cyclin-dependent kinase 2 ( Cdk2; IC = 1M) by blocking the ATP site.

Additional Information

Synonyms	4-(3'-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline, HCI
Product #	W-1044
CAS #	211555-08-7
Chemical Name	4-(3'-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline, HCI
Formula	C16 H15 N3 O3 . Cl H
MW	333.773
Appearance	Pale yellow Solid
Purity	97%
Solubility	Soluble in DMSO
Storage Temp	+4°C
Use	WHI-P180, Hydrochloride is a potent inhibitor of lgE-mediated mast cell responses to allergens

Additional Information

MDL Number	MFCD09026915
InChI	InChI=1S/C16H15N3O3.ClH/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-4-3-5-11(20)6-10;/h3-9,20H,1-2H3,(H,17,18,19);1H
SMILES	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC.Cl