Product Information
| Purity: |
Affinity purification |
| Storage: |
Store at -20 or -80°C. Avoid freeze/thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Catalog No: A70020
Histone H3K79me2 Polyclonal Antibody
Application:
WB (1:500-1:1000), IHC (1:50-1:100), IF (1:50-1:200), IP (1:50-1:200), ChIP (1:50-1:200)
Cross-Reactivity: H, M, R, other (wide range)
Calculated MW: 16kDa
Species: Rabbit
Isotype: IgG
Purity: Affinity purification
Concentration: 1mg/mL
Storage:
Store at -20 or -80°C. Avoid freeze/thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Immunogen Information
Immunogen:
A synthetic peptide of human Histone H3K79me2
Gene ID: 8290
Swiss Prot: Q16695
Synonyms: H3.4; H3/g; H3FT; H3t; MGC126886; MGC126888
Background:
H3K79 methylation is one of the gene activation markers.? DOT1L methyltransferase usually involves in H3K79 methylation, playing essential roles in embryonic development, hematopoiesis, cardiac function and the development of leukemia.
To detect marker H3K79 methylation status, pick from our H3K79 polyclonal antibody series.
PDF:
SDS:
Reference:
1. Robert A Copeland. Protein methyltransferases in cancer. (2013) AACR Annual Meeting.
2. Roy M Pollock. Preclinical Characterization of a Potent, Selective Inhibitor of the Protein Methyltransferase DOT1L for Use in the Treatment of MLL-Rearranged Leukemia. (2012) 54th ASH Annual Meeting and Exposition.?
