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Anti-FAM120A Antibody

品牌：Antibodies

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規(guī)格：100μl

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Anti-FAM120A Antibody

商品詳情參考文獻相關(guān)資料

Overview

Name:	Anti-FAM120A Antibody See all FAM120A primary antibodies
Description:	Rabbit polyclonal antibody to FAM120A
Specificity:	This antibody will not cross-reacti with FAM120B / PGCC1.
Applications:	E, WB, IHC
Reactivity:	Human, Mouse, Rat
Immunogen:	Raised against an 18 amino acid peptide from near the center of human FAM120A.
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Affinity chromatography purified via peptide column
Formulation:	Supplied in PBS containing 0.02% sodium azide.
Storage:	Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target

Function:	Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II (By similarity). May participate in mRNA transport in the cytoplasm.
Tissue Specificity:	Present in Purkinje cells in the cerebellum, and in cortical neurons (at protein level).
Sequence Similarities:	Belongs to the constitutive coactivator of PPAR-gamma family.
Post-Translational Modification:	Arg-980 is dimethylated, probably to asymmetric dimethylarginine.
Cellular Location:	Cytoplasm. Cell membrane. Translocates to plasma membrane upon ultraviolet exposure.
Database Links:	Entrez Gene: 23196?Human Entrez Gene: 218236?Mouse Entrez Gene: 291019?Rat GenBank: NP_055427.2?Human Omim: 612265?Human SwissProt: Q9NZB2?Human SwissProt: Q6A0A9?Mouse Unigene: 372003?Human Unigene: 707324?Human Unigene: 426571?Mouse
Synonyms:	C9orf10 Antibody Chromosome 9 open reading frame 10 Antibody Constitutive coactivator of PPAR gamma like protein 1 Antibody Constitutive coactivator of PPAR-gamma-like protein 1 Antibody DNA polymerase transactivated protein 1 Antibody DNA polymerase transactivated protein 5 Antibody DNAPTP1 Antibody DNAPTP5 Antibody F120A_HUMAN Antibody FAM120A Antibody Family with sequence similarity 120A Antibody Hypothetical protein LOC23196 Antibody KIAA0183 Antibody LOC23196 Antibody MGC111527 Antibody MGC133257 Antibody OSSA Antibody Oxidative stress-associated Src activator Antibody Protein FAM120A Antibody
Information:	Target information shown above is from the UniProt Consortium.