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Anti-L-Ficolin (human) ABS 005-16

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貨號：ABS 005-16

規(guī)格：200 μg

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Anti-L-Ficolin (human)

商品詳情參考文獻相關(guān)資料

Cat. No.: ABS 005-16
Product name: Anti-L-Ficolin (human)
Description: Mouse monoclonal antibody
Specificity: L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease) (1).
Immunogen: Purified procaryot expressed recombinant human L-Ficolin and full-length L-Ficolin (Ficolin-2) protein?
Application: ELISA, WB
Species reactivity (positive): Human
Species reactivity (negative): Not determined
Subclass: IgG1/k
Gene ID: 2220
Clone number: 16
Epitope: Not determined
Content: Available in 200 μL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification: Protein-A purified
Form: Liquid
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8oC without exposure to light. No precautions necessary during handling.
Target: L-Ficolin (Ficolin-2) is an innate immunity pattern recognition molecule found in human serum. L-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP), such as carbohydrates (GlcNAc), lipoteichoic acid and acetylated groups thereby facilitating phagocytosis and activation of complement through the lectin route using the same serine proteases as mannose-binding lectin (MBL) named MASP ((MBL)-associated serine protease) (1).

Application 1: ELISA

ABS 005-16 is especially well suited as capture antibody in a sandwich ELISA in combination with ABS 005-19. Furthermore, in ELISA, ABS 005-16 reacts with recombinant L-Ficolin coated directly into the microtiter well (1).
Application 2: WB
ABS 005-16 can be used in Western blotting.

1. Munthe-Fog L, Hummelsh?j T, Hansen BE, Koch C, Madsen HO, Skj?dt K, Garred P (2007) The impact of FCN2 polymorphisms and haplotypes on the Ficolin-2 serum levels. Scand J Immunol 65:383-392.: 17386030

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