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P03999 – Iron oxide nano-emulsion

品牌：CheMatech

貨號(hào)：Preclinical MRI probes

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HomePreclinical MRI probesP03999 – Iron oxide nano-emulsion P03999 – Iron oxide nano-emulsion 580.00 €? Category: Preclinical MRI probes?

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P03999 – Iron oxide nano-emulsion

580.00 €

Category: Preclinical MRI probes

Catalogue Number	P03999
Description	P03999 is the corresponding non-targeted P04000 (see P04000 description)
Main Applications	Evaluation of angiogenesis status, evaluation of anti-tumoral treatment follow up based on ανβ3-expression
Molecular characteristics	– Hydrodynamic size: diameter is 180 nm – Fe content: ~106 Fe atoms per particle – Recommended dose: 200 μmolFe/kg = 2.5 μL/g Example: for a 30g body weight mouse, injection volume is 75 μL – Recommended imaging time: up to 1h post injection (unbound contrast agent cleared from the blood) – Contrast mechanism: susceptibility effect – Histology: Perl’s staining – In vitro quantification techniques: P04000 is a Fe-based contrast agent. Thus, it is necessary to take into account the endogenous iron content for quantification in biological media by ICP-AES or ICP-MS. Another way for USPIO quantification is relaxometry, which is poorly sensitive to endogenous iron content.
Characteristics of the vial	– Concentration: [Fe] = 4.47 mgFe/mL – [Fe] = 80 mmol/L (MFe=56 g/mol) – Volume: 450 μL (5 mice dose approx.) – Other animal species: contact us
Storage	Need to be stored at 4°C in a closed vial away from light
Notes	For in vitro or animal use only
Selected publications